Hydrogel-Based Bio-Nanomachine Transmitters for Bacterial Molecular Communications

Martins, Daniel P. and O'Reilly, Huong Q. and Coffey, Lee and Cotter, Paul D. and Balasubramaniam, Sasitharan (2020) Hydrogel-Based Bio-Nanomachine Transmitters for Bacterial Molecular Communications. In: Proceedings of the 1st ACM International Workshop on Nanoscale Computing, Communication, and Applications.

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Official URL: https://doi.org/10.1145/3416006.3431271


Bacterial quorum sensing can be engineered with a view to the design of biotechnological applications based on their intrinsic role as a means of communication. We propose the creation of a positive feedback loop that will promote the emission of a superfolded green fluorescence protein from a bacterial population that will flow through hydrogel, which is used to encapsulate the cells. These engineered cells are heretofore referred to as bio-nanomachine transmitters and we show that for lower values of diffusion coefficient, a higher molecular output signal power can be produced, which supports the use of engineered bacteria contained within hydrogels for molecular communications systems. In addition, our wet lab results show the propagation of the molecular output signal, proving the feasibility of engineering a positive feedback loop to create a bio-nanomachine transmitter that can be used for biosensing applications.

Item Type: Conference or Workshop Item (Paper)
Uncontrolled Keywords: nanocommunications, engineered bacteria, bio-nanomachines
Departments or Groups: Walton Institute for Information and Communications Systems Science
Depositing User: Daniel Martins
Date Deposited: 24 Nov 2020 15:08
Last Modified: 24 Nov 2020 15:08
URI: https://repository.wit.ie/id/eprint/3476

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