Macular pigment and ocular biometry

Neelam, K. and Nolan, John and Loane, E. and Stack, J. and O'Donovan, O. and Eong, K. G. A. and Beatty, S. (2006) Macular pigment and ocular biometry. Vision Research, 46 (13). pp. 2149-2156.

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Abstract

This study is designed to investigate the relationship between macular pigment optical density (MPOD) and ocular biometric parameters. The following details were recorded for 180 healthy subjects: demographic profile; best-corrected visual acuity; refractive status; ocular biometric parameters [axial length (AL), anterior chamber depth (ACD), lens thickness (LT) and vitreous chamber depth (VCD)]; ocular dominance; MPOD; serum lutein (L) and zeaxanthin (Z). The mean MPOD (+/- SD) was 0.307 (0.155) and 0.305 (0.149) in the right and left eyes, respectively. No demonstrable relationship was observed between MPOD and AL, ACD or VCD [AL: r = 0.091, p = 0.225; ACD: r = 0.091, p = 0.227; VCD: r = 0.146, p = 0.051]. There was a significant and inverse relationship between LT and MPOD (r = -0.204; p = 0.008), which was attenuated to non-significance after correction for age and height (r = -0.058; p = 0.466). This study fails to identify an association between MPOD and ocular biometric parameters. This is an important negative finding, which allows investigators to study MP, and its relationship with potentially important variables, without the need to correct for ocular biontetric parameters. (c) 2005 Elsevier Ltd. All rights reserved.

Item Type: Article
Additional Information: ISI Document Delivery No.: 052QW English Article 0042-6989
Uncontrolled Keywords: macular pigment axial length anterior chamber depth lens thickness vitreous chamber depth Optical coherence tomography human crystalline lens tanjong-pagar survey axial length age thickness degeneration dimensions refraction lutein
Departments or Groups: Macular Pigment Research Group
Divisions: School of Science
Date Deposited: 15 Jul 2009 10:42
Last Modified: 22 Aug 2016 10:25
URI: http://repository.wit.ie/id/eprint/58

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