Martins, Daniel P. and O'Reilly, Huong Q. and Coffey, Lee and Cotter, Paul D. and Balasubramaniam, Sasitharan (2020) Hydrogel-based Bio-nanomachine Transmitters for Bacterial Molecular Communications. In: NanoCoCoA 2020 - Proceedings of the 1st ACM International Workshop on Nanoscale Computing, Communication, and Applications, Part of the 18th ACM Conference on Embedded Networked Sensor Systems, SenSys 2020 :. NanoCoCoA 2020 - Proceedings of the 1st ACM International Workshop on Nanoscale Computing, Communication, and Applications, Part of the 18th ACM Conference on Embedded Networked Sensor Systems, SenSys 2020 . Association for Computing Machinery (ACM), JPN, pp. 14-19. ISBN 9781450381161
Full text not available from this repository.Abstract
Bacterial quorum sensing can be engineered with a view to the design of biotechnological applications based on their intrinsic role as a means of communication. We propose the creation of a positive feedback loop that will promote the emission of a superfolded green fluorescence protein from a bacterial population that will flow through hydrogel, which is used to encapsulate the cells. These engineered cells are heretofore referred to as bio-nanomachine transmitters and we show that for lower values of diffusion coefficient, a higher molecular output signal power can be produced, which supports the use of engineered bacteria contained within hydrogels for molecular communications systems. In addition, our wet lab results show the propagation of the molecular output signal, proving the feasibility of engineering a positive feedback loop to create a bio-nanomachine transmitter that can be used for biosensing applications.
| Item Type: | Book Section |
|---|---|
| Additional Information: | Funding Information: This publication has emanated from research conducted with the financial support of Science Foundation Ireland (SFI) and the Department of Agriculture, Food and Marine on behalf of the Government of Ireland under Grant Number [16/RC/3835]-VistaMilk. Funding Information: This publication has emanated from research conducted with the financial support of Science Foundation Ireland (SFI) and the Department of Agriculture, Food and Marine on behalf of the Government of Ireland under Grant Number [16/RC/3835] - VistaMilk. Publisher Copyright: © 2020 ACM. |
| Uncontrolled Keywords: | /dk/atira/pure/subjectarea/asjc/2200/2207 |
| Departments or Groups: | |
| Depositing User: | Admin SSL |
| Date Deposited: | 09 Jan 2024 10:15 |
| Last Modified: | 27 Apr 2024 23:01 |
| URI: | https://repository.wit.ie/id/eprint/7756 |
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