Cregg, P J and Murphy, Kieran and Mardinoglu, Adil (2007) Calculation of nanoparticle capture efficiency in magnetic drug targeting. Journal of Magnetism and Magnetic Materials. ISSN 03048853 (Submitted)
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Abstract
The magnetic targeted drug delivery system of Aviles, Ebner and Ritter, which uses high gradient magnetic separation (HGMS) is considered. In that model large ferromagnetic particles are used as seeds to aid collection of multiple domain nanoparticles (radius ≈ 200nm. Here, in contrast, single domain magnetic nanoparticles(radius in 20–100 nm) are considered and the Langevin function is used to describe the magnetization. Simulations based on this model were performed using the open source C++ finite volume library OpenFOAM. The simulations indicate that use ofthe Langevin function predicts greater collection efficiency than might be otherwise expected.
| Item Type: | Article |
|---|---|
| Departments or Groups: | Materials Characterisation and Processing Group |
| Divisions: | School of Engineering > Department of Engineering Technology School of Science > Department of Computing, Maths and Physics |
| Depositing User: | P.J. Cregg |
| Date Deposited: | 01 Feb 2008 09:38 |
| Last Modified: | 23 Jun 2021 15:18 |
| URI: | https://repository.wit.ie/id/eprint/910 |
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